Low dosage and long treatment duration of beta-lactam: risk factors for carriage of penicillin-resistant Streptococcus pneumoniae.

@article{Guillemot1998LowDA,
  title={Low dosage and long treatment duration of beta-lactam: risk factors for carriage of penicillin-resistant Streptococcus pneumoniae.},
  author={Didier Guillemot and Claude Carbon and Beverley Balkau and Pierre Geslin and Herv{\'e} Lecoeur and Françoise Vauzelle-Kervro{\"e}dan and Gilles M. Bouvenot and Eveline Eschw{\`e}ge},
  journal={JAMA},
  year={1998},
  volume={279 5},
  pages={
          365-70
        }
}
CONTEXT The spread of drug-resistant Streptococcus pneumoniae in the community is a public health problem in developed and developing nations, but whether antibiotic use is responsible for the increase in drug resistance is not known. OBJECTIVE To analyze the relationship between penicillin-resistant S pneumoniae (PRSp) pharyngeal carriage and characteristics of beta-lactam use. DESIGN Observational study of children attending 20 randomly sampled schools. SETTING The Loiret, in the center… CONTINUE READING
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