Low-density lipoproteins from embryonic cerebrospinal fluid are required for neural differentiation.

@article{Parada2008LowdensityLF,
  title={Low-density lipoproteins from embryonic cerebrospinal fluid are required for neural differentiation.},
  author={Carolina Parada and Joan Carles Escol{\`a}-Gil and David L{\'o}pez Bueno},
  journal={Journal of neuroscience research},
  year={2008},
  volume={86 12},
  pages={2674-84}
}
During development, embryonic cerebrospinal fluid(E-CSF) is involved in cell survival, proliferation, and neurogenesis of the neuroepithelial progenitor cells. We have recently identified a complex pattern of proteins in chick and rat E-CSF, which include apolipoproteins. Apolipoproteins play a critical role in the function of lipoproteins by interacting with receptors to deliver the lipid cargo to target cells. However, the function of these E-CSF apolipoproteins is unclear. Here, we… CONTINUE READING

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