Corpus ID: 30451070

Low density lipoprotein receptor activity in human intracranial tumors and its relation to the cholesterol requirement.

@article{Rudling1990LowDL,
  title={Low density lipoprotein receptor activity in human intracranial tumors and its relation to the cholesterol requirement.},
  author={Mats Rudling and Bo Angelin and C O Peterson and Vincent Peter Collins},
  journal={Cancer research},
  year={1990},
  volume={50 3},
  pages={
          483-7
        }
}
  • Mats Rudling, Bo Angelin, +1 author Vincent Peter Collins
  • Published in Cancer research 1990
  • Medicine
  • The receptor binding of low density lipoprotein (LDL) was determined in homogenates of surgically removed specimens from primary and metastatic intracranial tumors and in some cases also from surrounding brain. Seventy-one specimens from 63 patients were analyzed. In a subsample of 16 specimens from 13 patients, the activity of 3-hydroxy-3-methylglutaryl-CoA reductase was assayed in parallel. The LDL binding in the tumors varied over a wide range. A significantly higher LDL binding activity was… CONTINUE READING

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