Low density lipoprotein inhibits accumulation of nitrites in murine brain endothelial cell cultures.

@article{Bereta1992LowDL,
  title={Low density lipoprotein inhibits accumulation of nitrites in murine brain endothelial cell cultures.},
  author={Michal Bereta and Joanna Bereta and Sharon R Cohen and Marion C Cohen},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={186 1},
  pages={315-20}
}
Endothelial cells produce nitric oxide which is considered to serve as a major source of endothelial derived relaxing factor activity. It has been demonstrated that activation of mouse brain endothelium by TNF-alpha and IFN-gamma led to accumulation of nitrite which is presumably formed by oxidation of nitric oxide. A number of studies suggest that reactive… CONTINUE READING