Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis

@inproceedings{Graf2012LowCN,
  title={Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis},
  author={Scott W Graf and Susan Elizabeth Lester and Johannes C Nossent and Catherine L Hill and Susanna M Proudman and Anita T Y Lee and Maureen Rischmueller},
  booktitle={Arthritis research & therapy},
  year={2012}
}
INTRODUCTION Low copy number (CN) of the Fc gamma receptor 3B (FCGR3B) gene has been associated with systemic autoimmune disease. This receptor for IgG is present almost exclusively on neutrophils and plays a role in their interaction with immune complexes. At present the relationship between FCGR3B and rheumatoid arthritis (RA) is unclear. The aim of the present study was to investigate whether low CN of the FCGR3B gene is associated with susceptibility to RA. METHOD The FCGR3B CN was… CONTINUE READING