Low circulating levels of ProMMP-2 are associated with adverse prognosis in bladder cancer.

@article{Vasala2008LowCL,
  title={Low circulating levels of ProMMP-2 are associated with adverse prognosis in bladder cancer.},
  author={Kaija Vasala and Paula Kuvaja and Taina Turpeenniemi-Hujanen},
  journal={Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine},
  year={2008},
  volume={29 5},
  pages={279-86}
}
OBJECTIVES In this study the serum levels of proMMP-2, active MMP-2, TIMP-2 and MMP-2:TIMP2 complex were evaluated. We also studied the correlation of these parameters with clinicopathological parameters in patients suffering from bladder carcinoma and outcome in this patient group. METHODS The levels of circulating proMMP-2, active MMP-2, proMMP-9, TIMP-1, TIMP-2 and MMP-2:TIMP-2 complex of 84 patients with bladder cancer were measured by ELISA. The proMMP-2 and TIMP-2 immunoreactive… CONTINUE READING

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