Low chloride-dependent release of taurine by a furosemide-sensitive process in the in vivo rat hippocampus.

Extracellular amino acid levels and field potentials evoked by perforant pathway stimuli were studied in vivo by means of a dialysis device, perfusing the rat dentate gyrus with low chloride solutions. When balanced with acetate, these perfusions enhanced the granule cell population spike amplitude. A specific extracellular taurine enhancement occurred… CONTINUE READING