Low catalyst loading ligand-free palladium-catalyzed direct arylation of furans: an economically and environmentally attractive access to 5-arylfurans

@article{Dong2009LowCL,
  title={Low catalyst loading ligand-free palladium-catalyzed direct arylation of furans: an economically and environmentally attractive access to 5-arylfurans},
  author={Jia Jia Dong and Julien Roger and Franc Po{\vz}gan and Henri Doucet},
  journal={Green Chemistry},
  year={2009},
  volume={11},
  pages={1832-1846}
}
The direct 5-arylation of furans at very low catalyst loading using Pd(OAc)2 as catalyst without added ligand proceed in high yields. Turnover numbers up to 10000 have been obtained for the coupling of several activated aryl bromides. A wide range of functions on the furan or aryl bromide is tolerated. 
75 Citations
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