Low-carbohydrate diets and men's cortisol and testosterone: Systematic review and meta-analysis.

  title={Low-carbohydrate diets and men's cortisol and testosterone: Systematic review and meta-analysis.},
  author={Joseph Whittaker and Miranda Harris},
  journal={Nutrition and health},
Background: Low-carbohydrate diets may have endocrine effects, although individual studies are conflicting. Therefore, a review was conducted on the effects of low- versus high-carbohydrate diets on men's testosterone and cortisol. Methods: The review was registered on PROSPERO (CRD42021255957). The inclusion criteria were: intervention study, healthy adult males, and low-carbohydrate diet: ≤35% carbohydrate. Eight databases were searched from conception to May 2021. Cochrane's risk of bias… 
2 Citations

Figures from this paper

Obesity, type 2 diabetes, and testosterone in ageing men

The magnitude of weight loss is linearly associated with an increase in serum testosterone concentration and with the likelihood of preventing T2D or reverting newly diagnosed disease; treatment with testosterone for 2 years increases the probability of a positive outcome from a lifestyle intervention alone by approximately 40%.

Ketogenic state improves testosterone serum levels-results from a systematic review and meta-analysis.

Comprehensively, KD improved testosterone levels depending on both patients' age and KD-induced weight loss, but the lack of information in included studies on hormones of the hypothalamic-pituitary-gonadal axis prevents an exhaustive comprehension about mechanisms connecting ketosis and testosterone homeostasis.



Low-fat diets and testosterone in men: Systematic review and meta-analysis of intervention studies

Low-Carbohydrate Diets and All-Cause Mortality: A Systematic Review and Meta-Analysis of Observational Studies

Low-carbohydrate diets were associated with a significantly higher risk of all-cause mortality and they were not significantly associated with the risk of CVD mortality and incidence.

The effects of low-carbohydrate diets on cardiovascular risk factors: A meta-analysis

This meta-analysis confirms that low-carbohydrate diets have a beneficial effect on cardiovascular risk factors but that the long-term effects on cardiovascularrisk factors require further research.

Body weight loss reverts obesity-associated hypogonadotropic hypogonadism: a systematic review and meta-analysis.

Weight loss is associated with an increase in both bound and unbound testosterone levels, and the normalization of sex hormones induced by body weight loss is a possible mechanism contributing to the beneficial effects of surgery in morbid obesity.

The effect of low-carbohydrate diet on the pattern of hormonal changes during incremental, graded exercise in young men.

The purpose of this study was to discover whether severe dietary carbohydrate (CHO) restriction modifies the relationship between exercise intensity and hormonal responses to exercise. Changes in the

Testosterone level and risk of type 2 diabetes in men: a systematic review and meta-analysis

A meta-analysis suggests that higher testosterone level can significantly decrease the risk of type 2 diabetes in men, and combined with previous researches, suggests a reverse-causality scenario in the relation between testosterone deficiency and risk of types 1 and 1A in men.

Ergogenic Properties of Ketogenic Diets in Normal-Weight Individuals: A Systematic Review

A review of existing evidence concerning the effect of KDs on body composition, aerobic and anaerobic capacity, muscle development, and sports performance in normal-weight individuals including athletes concludes that a non-calorie-restricted ketogenic diet provides minimal ergogenic benefits, but can be used to optimize body mass and composition without compromising athletic performance.

Nutritional modulation of exercise-induced immunodepression in athletes: a systematic review and meta-analysis

The available evidence failed to support a role for other nutritional supplements in preventing exercise-induced immune suppression and larger trials with clinically relevant and uniform end points are necessary to clarify the role of these nutritional interventions.