Low affinity purinergic receptor modulates the response of rat submandibular glands to carbachol and substance P.

@article{Mtioui1996LowAP,
  title={Low affinity purinergic receptor modulates the response of rat submandibular glands to carbachol and substance P.},
  author={Mourad M{\'e}tioui and H Amsallem and Eduardo Alzola and Noureddine Chaib and A Elyamani and Arie Moran and Aida Marino and J. P. Dehaye},
  journal={Journal of cellular physiology},
  year={1996},
  volume={168 2},
  pages={462-75}
}
The effect of extracellular ATP on the intracellular calcium concentration ([Ca2+]i) in rat submandibular glands was tested. The dose-response curve for ATP was biphasic with a first increase in the 1-30 microM concentration range and a further increase at concentrations higher than 100 microM. Among ATP analogs, only benzoyl-ATP stimulated the low affinity component. ATP tau S blocked this response. All the other analogs tested reproduced the high-affinity low capacity response. Magnesium and… CONTINUE READING
Highly Cited
This paper has 30 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…