Low affinity NGF receptor expression in the central nervous system during experimental allergic encephalomyelitis.

@article{Nataf1998LowAN,
  title={Low affinity NGF receptor expression in the central nervous system during experimental allergic encephalomyelitis.},
  author={Serge Nataf and Philippe Naveilhan and Laurence Sindji and Françoise Darcy and Philippe Brachet and Claudia N. Montero-Menei},
  journal={Journal of neuroscience research},
  year={1998},
  volume={52 1},
  pages={83-92}
}
In the central nervous system (CNS), p75, or low-affinity nerve growth factor receptor (LNGFR), is assumed to play a critical role in mediating the effects of neurotrophins on neuronal survival. Recent studies have shown that nerve growth factor (NGF) can act also on immune cells through its binding to p75. Using immunohistochemistry, we have investigated the expression of the p75 receptor in the CNS during chronic relapsing experimental allergic encephalomyelitis (EAE) of the Lewis rat, an… CONTINUE READING

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