Low activity of complement in the cerebrospinal fluid of the patients with various prion diseases

@inproceedings{Chen2016LowAO,
  title={Low activity of complement in the cerebrospinal fluid of the patients with various prion diseases},
  author={Cao Chen and Yan Chun Lv and Qi Shi and Wei Zhou and Kang Xiao and Jing Sun and Xiao-Dong Yang and Xiao-Ping Dong},
  booktitle={Infectious diseases of poverty},
  year={2016}
}
BackgroundThe aim of this study was to analyze the state of activity and levels of complement in the cerebrospinal fluid (CSF) of patients with various prion diseases (PrDs).FindingsThe proteomic data emphasized the levels of 20 known complement components found in the CSF of the sCJD panel that were lower than those found in the non-PrD panel. 50 % of the complement hemolytic activity (CH50) assays revealed significantly lower activity of complement in the CSF of the sCJD panel. The decreased… CONTINUE READING
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  • 2017
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