Low Temperature Selectively Inhibits Fusion Vesicles and Lysosomes During Heterophagy Perfused Rat Liver * Between Pinocytic of ' 251-Asialofetuin


Galactose-terminating ligands are specifically recognized by mammalian hepatocytes, internalized, and degraded within lysosomes. We have studied the ffects of temperature on this process using "%asialofetuin and the perfused rat liver. Uptake and catabolism of 'aaI-asialofetuin continued but were progressively slowed as the temperature decreased from 36°C… (More)

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