Low-Salt Diet Enhances Vascular Reactivity and Ca2+ Entry in Pregnant Rats With Normal and Reduced Uterine Perfusion Pressure

  title={Low-Salt Diet Enhances Vascular Reactivity and Ca2+ Entry in Pregnant Rats With Normal and Reduced Uterine Perfusion Pressure},
  author={Jena B. Giardina and Kathy L. Cockrell and Joey P. Granger and Raouf A. Khalil},
  journal={Hypertension: Journal of the American Heart Association},
Salt moderation is often recommended to prevent excessive increases in blood pressure during pregnancy, particularly in women who are prone to pregnancy-induced hypertension; however, the vascular effects of low dietary salt intake during pregnancy are unclear. We investigated whether a low-salt diet during pregnancy alters the mechanisms of vascular smooth muscle contraction. Active stress and 45Ca2+ influx were measured in endothelium-denuded aortic strips of virgin and normal pregnant… 

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