Low Plasma Cholinesterase Activities are Associated with Deficits in Spatial Orientation, Reduced Ability to Perform Basic Activities of Daily Living, and Low Body Mass Index in Patients with Progressed Alzheimer's Disease.

@article{Dingova2016LowPC,
  title={Low Plasma Cholinesterase Activities are Associated with Deficits in Spatial Orientation, Reduced Ability to Perform Basic Activities of Daily Living, and Low Body Mass Index in Patients with Progressed Alzheimer's Disease.},
  author={Dominika Dingova and Tomas Fazekas and Petra Okuliarova and Jaroslava Strbova and Matej Ku{\vc}era and Anna Hrabovsk{\'a}},
  journal={Journal of Alzheimer's disease : JAD},
  year={2016},
  volume={51 3},
  pages={801-13}
}
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder characterized by a central cholinergic deficit. Non-neuronal cholinergic changes are, however, described as well. Here we focused on possible changes in the activity of the plasma cholinesterases, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), in hospitalized AD patients. We analyzed plasma AChE and BChE activities with regards to age, gender, body mass index (BMI), cognitive functions, and… CONTINUE READING
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