Low-Mr heparin is as potent as conventional heparin in releasing lipoprotein lipase, but is less effective in preventing hepatic clearance of the enzyme.

Abstract

This study compares a low-Mr heparin preparation with conventional heparin with respect to its interaction with lipoprotein lipase (LPL) in vitro and its effects on the enzyme in vivo. Both heparin preparations were polydisperse in binding to LPL, but on average the low-Mr preparation showed lower affinity. Thus both conventional and low-Mr heparin bound… (More)

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@article{Liu1991LowMrHI, title={Low-Mr heparin is as potent as conventional heparin in releasing lipoprotein lipase, but is less effective in preventing hepatic clearance of the enzyme.}, author={Guang-ze Liu and Gunilla Bengtsson-Olivecrona and Per B Ostergaard and Thomas Olivecrona}, journal={The Biochemical journal}, year={1991}, volume={273 ( Pt 3)}, pages={747-52} }