Corpus ID: 14014796

Low Dose and Long Term Toxicity of Sodium Arsenite Caused Caspase Dependent Apoptosis Based on Morphology and Biochemical Character

  title={Low Dose and Long Term Toxicity of Sodium Arsenite Caused Caspase Dependent Apoptosis Based on Morphology and Biochemical Character},
  author={M. H. Abnosi and Zahra Jafari Yazdi},
  journal={Cell Journal (Yakhteh)},
  pages={161 - 170}
  • M. H. Abnosi, Zahra Jafari Yazdi
  • Published 2012
  • Biology, Medicine
  • Cell Journal (Yakhteh)
  • Objective: Although arsenite is toxic it is currently recommended for the treatment of malignancies. In this study the effects of sub-micromolar concentrations of sodium arsenite on the viability, morphology and mechanism of cell death of rat bone marrow mesenchymal stem cells (BMCs) over 21 days was investigated. Materials and Methods: In this experimental study, BMCs were extracted in Dulbecco’s Modified Eagles Medium (DMEM) containing 15% of fetal bovine serum (FBS) and expanded till the 3rd… CONTINUE READING
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