Corpus ID: 52974945

Low-Dose Quetiapine in the Treatment of SSRI-Induced Bruxism and Mandibular Dystonia: Case Series

  title={Low-Dose Quetiapine in the Treatment of SSRI-Induced Bruxism and Mandibular Dystonia: Case Series},
  author={Atefeh Zandifar and Mohammad Reza Mohammadi and Rahim Badrfam},
  journal={Iranian Journal of Psychiatry},
  pages={227 - 229}
Objective: Selective serotonin reuptake inhibitors (SSRIs) have been the most widely used psychopharmacological agents prescribed for depression worldwide. Some adverse effects of SSRI drugs on central nervous system are insomnia and bruxism. These drugs also affect sleep. Quetiapine is used as adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD). It is a low- dose dibenzothiazepine with more potent 5-HT2 than D2 receptor-blocking properties that can be… Expand
Morning Awakening With Pain in Sleep Bruxers with Craniomandibular Disorders and Concomitant Use of Selective Serotonin Reuptake Inhibitors (Ssris): A Intra-Group Comparison Study
Introduction: Subjects with sleep bruxing behavior may present with morning awakening with pain in multiple anatomic areas. Awakening with pain may be influenced to a certain extent by previous orExpand
Medications and addictive substances potentially inducing or attenuating sleep bruxism and/or awake bruxism
There are insufficient evidence‐based data to draw definite conclusions concerning medications and addictive substances inducing or aggravating sleep Bruxism and/or awake bruxism as well as concerning medications attenuating sleep bruxISM and/ or awake bruXism. Expand


Use of buspirone in selective serotonin reuptake inhibitor-induced sleep bruxism
Buspirone, is an agonist of the 5-HT1A receptor that increases dopaminergic neuron, firing in the ventral tegmental area and increases the synaptic release of dopamine in the prefrontal cortex, and these effects ameliorate drug-induced bruxism. Expand
Fluoxetine-induced sleep bruxism in an adolescent treated with buspirone: a case report.
  • O. Sabuncuoğlu, Ozalp Ekinci, M. Berkem
  • Medicine
  • Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
  • 2009
A case history of an adolescent with fluoxetine-induced bruxism that was successfully treated with buspirone is reported, which supports the efficacy of a treatment strategy in adolescents, which has previously been reported only for adult patients. Expand
SSRI-associated nocturnal bruxism in four patients.
An association between serotonin selective reuptake inhibitor (SSRI) treatment and the onset or exacerbation of nocturnal bruxism is suggested and it is suggested that a decrease in SSRI dosage or the addition of buspirone may relieve SSRI-associatedNocturnal Bruxism. Expand
Buspirone as an antidote to SSRI-induced bruxism in 4 cases.
4 cases support the concept of buspirone acting as a full agonist at the presynaptic 5-HT1A somatodendritic receptors located on the cell bodies of raphe serotonergic neurons that project to the ventral tegmental area of the midbrain. Expand
The beneficial effect of trazodone treatment on escitalopram-associated nocturnal bruxism.
It is noteworthy that buspirone, a 5HT1A partial agonist, was reported to be effective in SSRI-associated NB, and a case of the beneficial effect of trazodone in the treatment of escitalopram- associated NB. Expand
Antidepressant-induced bruxism successfully treated with gabapentin.
The authors describe a case of bruxism likely induced by the antidepressant venlafaxine and successfully treated with gabapentin in a man with bipolar disorder, and conclude that bruXism secondary to antidepressant therapy may be common. Expand
Sertraline induced acute mandibular dystonia
A patient with a diagnosis of emotionally unstable personality disorder and depression who developed severe mandibular dystonia with sertraline in the absence of concurrent prescription of medications, which have potential action on the dopaminergic system is described. Expand
Buspirone in the Treatment of Fluoxetine-Induced Sleep Bruxism.
A 7-year-old child with separation anxiety disorder (SAD) who displayed sleep bruxism with fluoxetine treatment that disappeared with buspirone treatment is presented. Expand
Gabapentin Treatment in Bruxism Associated With Fluoxetine.
It is recommended that in children receiving a combination of stimulants and atypical antipsychotics, the stimulants should not be discontinued on weekends or given drug holidays without careful monitoring for dystonia. Expand
Sertraline induced mandibular dystonia and bruxism
A young female patient with a diagnosis of the moderate depressive episode who developed mandibular dystonia and bruxism with sertraline in the absence of concurrent prescription of medications, which have potential action on the dopaminergic system are described. Expand