Low-Dose Arsenic Compromises the Immune Response to Influenza A Infection in Vivo

  title={Low-Dose Arsenic Compromises the Immune Response to Influenza A Infection in Vivo},
  author={Courtney D. Kozul and Kenneth H. Ely and Richard I Enelow and Joshua W. Hamilton},
  booktitle={Environmental health perspectives},
BACKGROUND Arsenic exposure is a significant worldwide environmental health concern. We recently reported that 5-week exposure to environmentally relevant levels (10 and 100 ppb) of As in drinking water significantly altered components of the innate immune response in mouse lung, which we hypothesize is an important contributor to the increased risk of lung disease in exposed human populations. OBJECTIVES We investigated the effects of As exposure on respiratory influenza A (H1N1) virus… CONTINUE READING
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