Low Cell pH Depresses Peak Power in Rat Skeletal Muscle Fibres at Both 30 ° C and 15 ° C : Implications for Muscle Fatigue

@inproceedings{Knuth2016LowCP,
  title={Low Cell pH Depresses Peak Power in Rat Skeletal Muscle Fibres at Both 30 ° C and 15 ° C : Implications for Muscle Fatigue},
  author={Shannon T Knuth},
  year={2016}
}
Historically, an increase in intracellular H (decrease in cell pH) was thought to contribute to muscle fatigue by direct inhibition of the cross-bridge leading to a reduction in velocity and force. More recently, due to the observation that the effects were less at temperatures closer to those observed in vivo, the importance of H as a fatigue agent has been questioned. The purpose of this work was to re-evaluate the role of H in muscle fatigue by studying the effect of low pH (6.2) on force… CONTINUE READING

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