Low C24-OH and C22-OH sulfatides in human renal cell carcinoma.
@article{Kim2014LowCA, title={Low C24-OH and C22-OH sulfatides in human renal cell carcinoma.}, author={I. C. Kim and Geul Bang and Jeong Hwa Lee and K. Kim and Y. Kim and H. Kim and J. Chung}, journal={Journal of mass spectrometry : JMS}, year={2014}, volume={49 5}, pages={ 409-16 } }
Histopathologic diagnosis of renal cell carcinoma (RCC) may sometimes be difficult with small biopsy samples. We applied histology-directed matrix-assisted laser desorption/ionization mass spectrometry to RCC samples to evaluate whether and how lipid profiles are different between RCC and normal tissue. We evaluated 59 RCC samples and 24 adjacent normal tissue samples collected from patients who underwent surgery. Five peaks were significantly differently expressed (p < 10(-7)) between RCCs and… CONTINUE READING
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