Love makes smell blind: mating suppresses pheromone attraction in Drosophila females via Or65a olfactory neurons

@inproceedings{Lebreton2014LoveMS,
  title={Love makes smell blind: mating suppresses pheromone attraction in Drosophila females via Or65a olfactory neurons},
  author={S{\'e}bastien Lebreton and Veit Grabe and Aman B. Omondi and Rickard Ignell and Paul G Becher and Bill S. Hansson and Silke Sachse and Peter Witzgall},
  booktitle={Scientific reports},
  year={2014}
}
In Drosophila, the male sex pheromone cis-vaccenyl acetate (cVA) elicits aggregation and courtship, through the odorant receptor Or67d. Long-lasting exposure to cVA suppresses male courtship, via a second channel, Or65a. In females, the role of Or65a has not been studied. We show that, shortly after mating, Drosophila females are no longer attracted to cVA and that activation of olfactory sensory neurons (OSNs) expressing Or65a generates this behavioral switch: when silencing Or65a, mated… CONTINUE READING