Lovastatin inhibits diet induced atherosclerosis in F1B golden Syrian hamsters.

@article{Otto1995LovastatinID,
  title={Lovastatin inhibits diet induced atherosclerosis in F1B golden Syrian hamsters.},
  author={J. Otto and Jos{\'e} Mar{\`i}a Ordov{\`a}s and Donald Smith and D van Dongen and Robert James Nicolosi and Ernst J. Schaefer},
  journal={Atherosclerosis},
  year={1995},
  volume={114 1},
  pages={
          19-28
        }
}
3-Hydroxy-3-methylglutaryl-CoA (HMG CoA) reductase inhibitors are the drugs most commonly prescribed in the US to lower blood cholesterol. Previous studies have shown their efficacy in reducing plasma low density lipoprotein (LDL) cholesterol. However, little is known about their effects on preventing diet induced atherosclerosis. We have investigated the changes in lipoprotein profiles and extent of atherogenesis in hamsters (F1B strain) consuming an atherogenic diet with and without… CONTINUE READING

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