Lotifazole (F 1686), a non-steroidal anti-inflammatory agent with an unusual pharmacological spectrum

Abstract

Lotifazole (F 1686) — 4-phenyl-2-(2′, 2′, 2-trichloroethoxycarboxamido) thiazole — has a range of antiinflammatory activities in animals that differs from the activities of classic non-steroidal drugs. It reduces carrageenin-induced oedema in rats, UV-induced erythema in guinea pigs, and Arthus pleurisies in rats only at high doses. It does not affect… (More)
DOI: 10.1007/BF01966840

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