Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair

@inproceedings{Akhtar2015LostHB,
  title={Lost highway(s): barriers to postnatal cortical neurogenesis and implications for brain repair},
  author={Aslam Abbasi Akhtar and Joshua John Breunig},
  booktitle={Front. Cell. Neurosci.},
  year={2015}
}
The genesis of the cerebral cortex is a highly complex and tightly-orchestrated process of cell division, migration, maturation, and integration. Developmental missteps often have catastrophic consequences on cortical function. Further, the cerebral cortex, in which neurogenesis takes place almost exclusively prenatally, has a very poor capacity for replacement of neurons lost to injury or disease. A multitude of factors underlie this deficit, including the depletion of radial glia, the… CONTINUE READING
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