Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas

  title={Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas},
  author={Portia A. Kreiger and Yoshifumi Okada and Scott Simon and Lucy Balian Rorke and David N Louis and Jeffrey Alan Golden},
  journal={Acta Neuropathologica},
Pediatric oligodendrogliomas are rare neoplasms and have not been characterized extensively either pathologically or genetically. Given the recent interest in the significance of chromosomal losses in predicting the clinical course and in establishing uniform diagnoses of adult oligodendrogliomas, we reviewed the pathological and clinical features of a series of pediatric oligodendrogliomas and determined their 1p and 19q status using fluorescence in situ hybridization. Of 19 tumors originally… CONTINUE READING
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