Loss of the TGFß-Activating Integrin avß8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type

Abstract

Chronic intestinal parasite infection is a major global health problem, but mechanisms that promote chronicity are poorly understood. Here we describe a novel cellular and molecular pathway involved in the development of chronic intestinal parasite infection. We show that, early during development of chronic infection with the murine intestinal parasite… (More)

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@inproceedings{Worthington2013LossOT, title={Loss of the TGF\ss-Activating Integrin av\ss8 on Dendritic Cells Protects Mice from Chronic Intestinal Parasitic Infection via Control of Type}, author={John Worthington and Joanna E Klementowicz and Sayema Rahman and Beata I. Czajkowska and Catherine Smedley and Herman Waldmann and Tim Sparwasser and Richard K Grencis and Mark A. Travis}, year={2013} }