Loss of the Heparan Sulfate Sulfotransferase, Ndst1, in Mammary Epithelial Cells Selectively Blocks Lobuloalveolar Development in Mice

@inproceedings{Crawford2010LossOT,
  title={Loss of the Heparan Sulfate Sulfotransferase, Ndst1, in Mammary Epithelial Cells Selectively Blocks Lobuloalveolar Development in Mice},
  author={Brett E. Crawford and Omai B. Garner and Joseph R. Bishop and David Y. Zhang and Kevin T Bush and Sanjay K. Nigam and Jeffrey D Esko},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Considerable evidence indicates that heparan sulfate is essential for the development of tissues consisting of branching ducts and tubules. However, there are few examples where specific sulfate residues regulate a specific stage in the formation of such tissues. METHODOLOGY/PRINCIPAL FINDINGS We examined the role of heparan sulfation in mammary gland branching morphogenesis, lactation and lobuloalveolar development by inactivation of heparan sulfate GlcNAc N-deacetylase/N… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 78 references

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice

  • KU Wagner, K McAllister, T Ward, B Davis, R Wiseman
  • Transgenic Res
  • 2001
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…