Loss of the DnaK-DnaJ-GrpE chaperone system among the Aquificales.

@article{Warnecke2012LossOT,
  title={Loss of the DnaK-DnaJ-GrpE chaperone system among the Aquificales.},
  author={Tobias Warnecke},
  journal={Molecular biology and evolution},
  year={2012},
  volume={29 11},
  pages={
          3485-95
        }
}
The DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis in bacteria. It interacts both with nascent polypeptides and with proteins that have become unfolded, either funneling its clients toward the native state or ushering misfolded proteins into degradation. In line with its key role in protein folding, KJE has been considered an essential building block for a minimal bacterial genome and common to all bacteria. In this study, I present a rigorous survey of 1… CONTINUE READING
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SHOWING 1-10 OF 55 REFERENCES

DnaK functions as a central hub in the E. coli chaperone network.

VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Converging concepts of protein folding in vitro and in vivo

VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Convergent evolution of metabolic roles in bacterial co-symbionts of insects.

VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Diversity of 16S rRNA gene, ITS region and aclB gene of the Aquificales

VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL