Loss of substantia nigra hyperintensity on 7 Tesla MRI of Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy.

@article{Kim2016LossOS,
  title={Loss of substantia nigra hyperintensity on 7 Tesla MRI of Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy.},
  author={Jong-Min Kim and Hye-jin Jeong and Yun Jung Bae and Sung-yeon Park and Eunhee Kim and Seo Young Kang and Eung Seok Oh and Kyeong Joon Kim and Beom Seok Jeon and Sang Eun Kim and Zang-Hee Cho and Young Bo Kim},
  journal={Parkinsonism & related disorders},
  year={2016},
  volume={26},
  pages={
          47-54
        }
}
BACKGROUND Seven Tesla (7T) MRI can visualize anatomical alterations occurring in a hyperintense structure of the substantia nigra in Parkinson's disease (PD). OBJECTIVE We investigated whether 7T MRI can detect the loss of substantia nigra hyperintensity in patients with PD, multiple system atrophy (MSA), and progressive supranuclear palsy (PSP). METHODS Using 7T MRI, we evaluated 26 healthy subjects, 30 patients with PD, 7 patients with MSA, and 3 patients with PSP. Two blinded readers… CONTINUE READING
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