Loss of renal function following bone marrow transplantation: an analysis of angiotensin converting enzyme D/I polymorphism and other clinical risk factors

@article{Juckett2001LossOR,
  title={Loss of renal function following bone marrow transplantation: an analysis of angiotensin converting enzyme D/I polymorphism and other clinical risk factors},
  author={M B Juckett and Elizabeth G. Cohen and CA Keever-Taylor and Yan-hua Zheng and C Lawton and J T Moulder and J L Klein},
  journal={Bone Marrow Transplantation},
  year={2001},
  volume={27},
  pages={451-456}
}
Chronic renal failure is an acknowledged late complication of BMT. It is related to the intensive chemotherapy, radiation and supporting medications. Polymorphism in the angiotensin converting enzyme (ACE) gene is associated with progression of nephropathy caused by diabetes and IgA nephropathy. We sought to determine whether ACE genotype and other clinical factors were associated with loss of renal function after BMT. We determined the genotype of 106 adult allogeneic BMT recipients, who… CONTINUE READING

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