Loss of renal blood flow autoregulation in chronic glomerulonephritic rats.

Abstract

Autoregulation of renal blood flow (RBF) was investigated in subacute (2 mo) and chronic (18 mo) passive Heymann nephritis (PH-2, PH-18) and age-matched controls (C-2, C-18). RBF was significantly lower in PH-18 than in C-18 (3.7 +/- 0.4 vs. 4.7 +/- 0.5 ml.min-1.kidney-1; P less than 0.05), whereas the mean blood pressure (MAP) was similar. The creatinine… (More)

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