Loss of microRNA-205 expression is associated with melanoma progression

Abstract

In this study, we used formalin-fixed paraffin-embedded melanocytic tumors to demonstrate reproducible alterations in microRNA expression in nevi compared with melanomas using a microarray platform. We validated those results in an independent set of nevi and melanomas by quantitative RT-PCR. miR-205 demonstrated a statistically significant, progressive… (More)
DOI: 10.1038/labinvest.2012.62

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