Loss of homeostatic tension induces apoptosis in tendon cells: an in vitro study.

@article{Egerbacher2008LossOH,
  title={Loss of homeostatic tension induces apoptosis in tendon cells: an in vitro study.},
  author={Monika Egerbacher and Steven Paul Arnoczky and Oscar Caballero and Michael Lavagnino and Keri L. Gardner},
  journal={Clinical orthopaedics and related research},
  year={2008},
  volume={466 7},
  pages={1562-8}
}
Apoptosis (programmed cell death) has been identified as a histopathologic feature of tendinopathy. While the precise mechanism(s) that triggers the apoptotic cascade in tendon cells has not been identified, it has been theorized that loss of cellular homeostatic tension following microscopic damage to individual tendon fibrils could be the stimulus for… CONTINUE READING