Loss of heterozygosity on chromosome 18q in cohesive-type gastric cancer is associated with tumor progression and poor prognosis.

Abstract

Although loss of heterozygosity (LOH) on chromosome 18q is frequently found in gastric cancer, the clinical significance of this abnormality has not been well documented. We examined LOH on chromosome 18q22-23 in DNA extracted from the tissues of gastric cancer patients using the PCR-based dinucleotide repeat assay with two microsatellite markers, D18S61… (More)

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@article{Inoue1998LossOH, title={Loss of heterozygosity on chromosome 18q in cohesive-type gastric cancer is associated with tumor progression and poor prognosis.}, author={T. Inoue and Shinya Uchino and N. Shiraishi and Y. Adachi and Satsuki Kitano}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={1998}, volume={4 4}, pages={973-7} }