Loss of heterozygosity of selected tumor suppressor genes in parathyroid carcinoma.

Abstract

BACKGROUND The histologic diagnosis of parathyroid carcinoma (PC) is challenging. We evaluated a large PC series for loss of heterozygosity (LOH) of selected tumor suppressor genes with histopathologic correlation. METHODS Among 2,238 patients explored for primary hyperparathyroidism (PHP), the cytoarchitectural parameters of 60 patients with surgical and… (More)
DOI: 10.1016/j.surg.2008.08.030

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