Loss of heterozygosity in follicular and papillary thyroid carcinomas.

  title={Loss of heterozygosity in follicular and papillary thyroid carcinomas.},
  author={Ana Rodrigues-Serpa and Ana Lui{\'i}sa Catarino and Jorge Fernando Maxnuck Soares},
  journal={Cancer genetics and cytogenetics},
  volume={141 1},
In this study we aimed at investigating the incidence and the role of 3p deletions, particularly at the 3p25 approximately pter region, in follicle cell-derived thyroid neoplasms, by using loss of heterozygosity (LOH) analysis. We analyzed 12 follicular adenomas (FA), 13 follicular thyroid carcinomas (FTC), and 15 papillary thyroid carcinomas (PTC) with 11 microsatellite markers for chromosome 3. One additional marker on 3q25.2 was also investigated for assessment of deletion extent on 3q… CONTINUE READING
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