Loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in Taiwan

@inproceedings{Sheu1999LossOH,
  title={Loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in Taiwan},
  author={J. C. Sheu and Y. Lin and H-C Chou and G S Huang and H-S Lee and Y-H Lin and S P Huang and Chih-Hao Chen and Jann-Tay Wang and P-H Lee and J Lin and F J Lu and D Chen},
  booktitle={British Journal of Cancer},
  year={1999}
}
SummaryElucidation of the basic genetic changes of human hepatocellular carcinoma is important for the understanding and treatment of this cancer. We used microsatellite polymorphism markers to study 30 cases of hepatocellular carcinoma (34 tumours) on all human chromosomes. DNA from 34 pairs of hepatocellular carcinomas and corresponding non-tumour parts was prepared. Loss of heterozygosity (LOH) and microsatellite instability on 23 chromosomes were investigated by 231 sets of microsatellite… CONTINUE READING