Loss of glutathione, ascorbate recycling, and free radical scavenging in human erythrocytes exposed to filtered cigarette smoke.

@article{Maranzana1998LossOG,
  title={Loss of glutathione, ascorbate recycling, and free radical scavenging in human erythrocytes exposed to filtered cigarette smoke.},
  author={Aldo Maranzana and Rolf J. Mehlhorn},
  journal={Archives of biochemistry and biophysics},
  year={1998},
  volume={350 2},
  pages={169-82}
}
Exposure of human erythrocytes to filtered cigarette smoke in vitro inhibited their capacity to reduce dehydroascorbic acid (ascorbate recycling activity). Glucose uptake was not affected, implying that dehydroascorbic acid transport was not inhibited by the smoke treatment. The intracellular reduction of cationic nitroxide free radicals, which provides a measure of ascorbate recycling, was also inhibited by cigarette smoke. A major factor in the inhibition of free radical reduction was… CONTINUE READING
Highly Cited
This paper has 23 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Hydrogen Sulfide and Cellular Redox Homeostasis

Oxidative medicine and cellular longevity • 2016
View 9 Excerpts
Highly Influenced

The role for N-acetylcysteine in the management of COPD

International journal of chronic obstructive pulmonary disease • 2006

Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease.

American journal of physiology. Lung cellular and molecular physiology • 1999
View 1 Excerpt

Similar Papers

Loading similar papers…