Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival.

@article{Mellitzer2010LossOE,
  title={Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival.},
  author={Georg Mellitzer and Anthony Beucher and Viviane Lobstein and Pascal Michel and Sylvie Robine and Mich{\`e}le Kedinger and G{\'e}rard Gradwohl},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 5},
  pages={1708-21}
}
At least 10 enteroendocrine cell types have been identified, and the peptide hormones they secrete have diverse functions that include regulation of glucose homeostasis, food intake, and gastric emptying. Mice lacking individual enteroendocrine hormones, their receptors, or combinations of these have shed light on the role of these hormones in the regulation of energy homeostasis. However, because enteroendocrine hormones have partially overlapping functions, these loss-of-function studies… CONTINUE READING