• DOI:10.1016/S0361-9230(02)00944-9
Corpus ID: 21785451

Loss of dendritic connectivity in CA1, CA2, and CA3 neurons in hippocampus in rat under aluminum toxicity: Antidotal effect of pyridoxine

@article{Sreekumaran2003LossOD,
  title={Loss of dendritic connectivity in CA1, CA2, and CA3 neurons in hippocampus in rat under aluminum toxicity: Antidotal effect of pyridoxine},
  author={E. Sreekumaran and T. Ramakrishna and T. Madhav and D. Anandh and T. Raju},
  journal={Brain Research Bulletin},
  year={2003},
  volume={59},
  pages={421-427}
}

E. Sreekumaran, T. Ramakrishna, +2 authors T. Raju

Published 2003

Biology, Medicine

Brain Research Bulletin

Aluminum chloride (AlCl(3); 4 mg/kg) was injected into the cerebrospinal fluid of adult rats as a one time dose. Rapid Golgi stained sections of hippocampus were examined for detailed histology of neurons in CA1, CA2, and CA3 areas. The axonal length and number of dendritic branches were seen reduced 30 days later in aluminum (Al)-injected group when compared to vehicle-injected controls. Of these perturbations, dendritic branches were seen reduced significantly. Al toxicity apparently affects… CONTINUE READING

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