Loss of corneal epithelial stem cell properties in outgrowths from human limbal explants cultured on intact amniotic membrane.

@article{Kolli2008LossOC,
  title={Loss of corneal epithelial stem cell properties in outgrowths from human limbal explants cultured on intact amniotic membrane.},
  author={Sai Kolli and M. Lako and F. Figueiredo and H. Mudhar and S. Ahmad},
  journal={Regenerative medicine},
  year={2008},
  volume={3 3},
  pages={
          329-42
        }
}
  • Sai Kolli, M. Lako, +2 authors S. Ahmad
  • Published 2008
  • Biology, Medicine
  • Regenerative medicine
  • BACKGROUND The corneal epithelium is renewed by stem cells located at the limbus, the so-called limbal stem cells (LSCs). Absence, damage or loss of the LSC population leads to the painful and blinding condition of LSC deficiency (LSCD). Ex vivo expansion of LSCs is an increasingly well recognized treatment modality for LSCD. One method of ex vivo expansion of LSCs involves the culture of limbal explants on amniotic membrane (AM). The purpose of this study was to analyze the outgrowths from… CONTINUE READING
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