Loss of connexin36 increases retinal cell vulnerability to secondary cell loss.

@article{Striedinger2005LossOC,
  title={Loss of connexin36 increases retinal cell vulnerability to secondary cell loss.},
  author={Katharine Striedinger and Elisabeth Petrasch-Parwez and Georg Zoidl and Markus Napirei and Carola Meier and Ulf T. Eysel and Rolf Dermietzel},
  journal={The European journal of neuroscience},
  year={2005},
  volume={22 3},
  pages={605-16}
}
Accruing evidence indicates that gap junctions are involved in neuronal survival after brain injury. The present study was aimed at clarifying the contribution of the neuronal gap-junction protein connexin36 (Cx36) to secondary cell loss after injury in the mouse retina. A focal retinal lesion was induced by infrared laser photocoagulation. Remarkably, this model allowed spatial and temporal definition of the lesion with high reproducibility. Moreover, Cx36 is abundantly expressed in the retina… CONTINUE READING

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