Loss of allelic heterozygosity at the harveyras locus in human oral carcinomas


The Harveyras locus was examined for restriction fragment polymorphism and loss of allelic heterozygosity in 62 oral cancer patients. Southern blot analysis onBamHI digests of the tumour tissue DNA, revealed 23 patients with H-ras-1 heterozygosity. The probes used to study the polymorphism were theBamHI 6.6-kb fragment encoding the complete H-ras-1 sequence… (More)
DOI: 10.1007/BF01612771


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