Loss of T cells influences sex differences in behavior and brain structure.

Abstract

Clinical and animal studies demonstrate that immune-brain communication influences behavior and brain function. Mice lacking T cell receptor β and δ chains were tested in the elevated plus maze, open field, and light-dark test and showed reduced anxiety-like behavior compared to wild type. Interestingly sex differences were observed in the behavioural… (More)
DOI: 10.1016/j.bbi.2015.02.016

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