Loss of STAT1 in Bone Marrow-Derived Cells Accelerates Skeletal Muscle Regeneration

@inproceedings{Gao2012LossOS,
  title={Loss of STAT1 in Bone Marrow-Derived Cells Accelerates Skeletal Muscle Regeneration},
  author={Yan Gao and Yanfeng Li and Xing Zhou Guo and Zhenguo Wu and Wei Zhang},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Skeletal muscle regeneration is a complex process which is not yet completely understood. Evidence suggested that the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway may have a role in myogenesis. In this study, we aim to explore the possible role of STAT1 in muscle regeneration. METHODS Wild-type and STAT1 knockout mice were used in this study. Tibialis anterior muscle injury was conducted by cardiotoxin (CTX) injection. Bone marrow… CONTINUE READING

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