Loss of SED1/MFG-E8 results in altered luminal physiology in the epididymis.

@article{Raymond2010LossOS,
  title={Loss of SED1/MFG-E8 results in altered luminal physiology in the epididymis.},
  author={Adam S Raymond and B Laurel Elder and Michael A. Ensslin and Barry D. Shur},
  journal={Molecular reproduction and development},
  year={2010},
  volume={77 6},
  pages={550-63}
}
SED1/MFG-E8, herein referred to as SED1, is a bimotif adhesive protein with ascribed functions in a range of cell-cell interactions, including sperm-egg binding. In the male reproductive tract, SED1 is secreted by the initial segment of the epididymis, where it coats sperm and subsequently facilitates binding to the egg zona pellucida. We have recently… CONTINUE READING