Loss of RAB25 expression in breast cancer.

@article{Cheng2006LossOR,
  title={Loss of RAB25 expression in breast cancer.},
  author={Ji-Ming Cheng and Ming Ding and Ahmed Aribi and Prabodh L. Shah and Krishna Rao},
  journal={International journal of cancer},
  year={2006},
  volume={118 12},
  pages={
          2957-64
        }
}
A novel breast cancer cell line (RAO-3) was established by transduction of the Q61L mutant RAS into human mammary epithelial cells that were immortalized with catalytic subunit of telomerase (hTERT). The cells displayed anchorage-independent growth and proliferation, and formed human mammary spindle cell carcinoma when injected into nude mice. Chromosome locus 1q22-23 was partially duplicated and inverted on one of the 3 chromosomes present in the cell line. We report here that mutations of… CONTINUE READING
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