Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice

Abstract

Lysyl oxidase-like 3 (LOXL3), a human disease gene candidate, is a member of the lysyl oxidase (LOX) family and is indispensable for mouse palatogenesis and vertebral column development. Our previous study showed that the loss of LOXL3 resulted in a severe cleft palate and spinal deformity. In this study, we investigated a possible role for LOXL3 in mouse… (More)
DOI: 10.1038/srep33856

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