Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT2C receptor dysfunction, and anhedonia in mice.

@article{Yamamoto2017LossOG,
  title={Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT2C receptor dysfunction, and anhedonia in mice.},
  author={Hideko Yamamoto and Etsuko Kamegaya and Yoko Hagino and Yukio Takamatsu and Wakako Sawada and Maaya Matsuzawa and Soichiro Ide and Toshifumi Yamamoto and Masayoshi Mishina and Kazutaka Ikeda},
  journal={Neuropharmacology},
  year={2017},
  volume={112 Pt A},
  pages={188-197}
}
The N-methyl-d-aspartate (NMDA) receptor channel is involved in various physiological functions, including learning and memory. The GluN2D subunit of the NMDA receptor has low expression in the mature brain, and its role is not fully understood. In the present study, the effects of GluN2D subunit deficiency on emotional and cognitive function were… CONTINUE READING